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Columnar simple epithelium of an apocrine sweat gland. Some secretory granules are located above the nucleus. A binucleated cell appear in the center of the image.

TEM micrograph showing a binucleated hepatocyte with many mitochondria and elongated cisterns of rough endoplasmic reticulum (RER). The space of Disse full of microvilli appear at three corners

Liver cells or hepatocytes showing a large nucleolus stained with eosin. There are two hepatocytes with large nucleus and three binucleated hepatocytes. These cells are polyploid.

High magnification micrograph of liver cells or hepatocytes showing a large nucleolus stained with eosin. There is a hepatocyte with a large nucleus and other binucleated. These cells are polyploid.

Binucleated mesothelioma cell in pleural fluid

Binucleated striated cardiac myocytes showing yellow pigment lipofuscin granules near the central nuclei. The myocytes are joined by intercalated disks. Light micrograph. HE stain.

Binucleated striated cardiac myocytes showing yellow pigment lipofuscin granules near the central nuclei. The myocytes are joined by intercalated disks. Light micrograph. H&E stain.

Columnar simple epithelium of an apocrine sweat gland, showing secretory granules above the nuclei and a binucleated cell. Near the base of the epithelium appear cross sections of myoepithelial cells,

Hepatic lobule showing dilated sinusoids full of red blood cells (congestion). Many hepatocytes are binucleated or show larger nuclei (polyploid).

Mucosa of urinary bladder lined by transitional epithelium (urothelium) resting on a connective tissue lamina propria. The superficial layer shows large cells with big nuclei (one of them binucleated)

Mucosa of urinary bladder lined by transitional epithelium (urothelium). The superficial layer shows large cells with big nuclei, sometimes binucleated.

High magnification micrograph of liver cells or hepatocytes showing a large nucleolus stained with eosin. In the center, a hepatocyte with a large nucleus, probably a polyploid cell.

TEM micrograph showing hepatocyte plates located among three sinusoids. The hepatocyte cytoplasm shows many mitochondria and cisterns of RER and microvilli in Disse space around sinusoids

light microscope view of liver cells

Liver stained with H&E. Many of the hepatocytes show two nuclei or they have a very large nucleus. These cells are polyploid cells. The hepatocytes also contain abundant granules of bile pigment.

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